General Information
    • ISSN: 2010-0221
    • Frequency: Bimonthly
    • DOI: 10.18178/IJCEA
    • Editor-in-Chief: Prof. Dr. Shen-Ming Chen
    • Executive Editor: Mr. Ron C. Wu
    • Abstracting/ Indexing: Chemical Abstracts Services (CAS), Ulrich's Periodicals Directory, CABI, DOAJ, Electronic Journals Library, Google Scholar, ProQuest, and Crossref
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Editor-in-chief
Prof. Dr. Shen-Ming Chen
National Taipei University of Technology, Taiwan
 

IJCEA 2013 Vol.4(4): 238-240 ISSN: 2010-0221
DOI: 10.7763/IJCEA.2013.V4.303

The Synthesis of Pyrazole Derivatives Based on Glucose

Kui Du, Yi-Jia Mei, Xian-Ting Cao, Peng-Fei Zhang, and Hui Zheng
Abstract—Heterocyclic compounds and glucose derivatives play important role in organic chemistry and biological chemistry for their richc functionality. A facile and convient protocol had been developed for the synthesis of a series of novel glucosyl pyrazole derivatives starting from D-glucose. The protected glucose by O-pivaloyl groups reacted with BTC and obtained corresponding 2-isocyanate glucose, which effectively avoid the harsh conditions and highly toxic agents compared to the traditional method. Glucosyl pyrazole derivatives were then prepared through the reaction of pyrazole and its derivatives with 2-isocyanate glucose with good yields.

Index Terms—Heterocycle, glucose, pyrazole, synthesis.

The authors are with the Hangzhou Normal University, Hangzhou 310036 China (e-mail: 584892598@qq.com, 562818116@qq.com, 459209401@qq.com, 1304112697@qq.com, huizheng@hznu.edu.cn).

[PDF]

Cite:Kui Du, Yi-Jia Mei, Xian-Ting Cao, Peng-Fei Zhang, and Hui Zheng, "The Synthesis of Pyrazole Derivatives Based on Glucose," International Journal of Chemical Engineering and Applications vol. 4, no. 4 pp. 页码, 2013.

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