General Information
    • ISSN: 2010-0221
    • Frequency: Bimonthly
    • DOI: 10.18178/IJCEA
    • Editor-in-Chief: Prof. Dr. Shen-Ming Chen
    • Executive Editor: Mr. Ron C. Wu
    • Abstracting/ Indexing: Chemical Abstracts Services (CAS), Ulrich's Periodicals Directory, CABI, DOAJ, Electronic Journals Library, Google Scholar, ProQuest, and Crossref
    • E-mail: ijcea@ejournal.net
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Editor-in-chief
Prof. Dr. Shen-Ming Chen
National Taipei University of Technology, Taiwan
 

IJCEA 2014 Vol.5(2): 109-111 ISSN: 2010-0221
DOI: 10.7763/IJCEA.2014.V5.361

Develop New Approaches to the Synthesis of N, N, N-triethyl-4-[(Hexahydro-2-oxo-1H-azepin-1-yl) Carbonyl]-Bromine/Chloride

Weijian Chen and Yujie Ren
Abstract—New approaches have been developed here: 4-methyl-benzoic acid first reacted with thionyl chloride, then with caprolactam, and last with N-bromosuccinimide to produce the 4-bromomethyl benzoyl caprolactam. Further, N, N, N-triethyl-4-[(hexahydro-2-oxo-1H-azepin-1-yl) carbonyl]-, Bromine was prepared through the reaction with triethylamine and 4-bromomethyl benzoyl caprolactam. The total yield was 61%. 4-methyl-benzoic acid reacted N-bromosuccinimide, then with chlorohydric acid, and last with caprolactam to produce 4 - chloromethyl benzoyl caprolactam. N, N, N-triethyl-4-[( hexahydro -2-oxo-1H-azepin-1-yl) carbonyl]-,Chloride was further synthesized via the reaction with triethylamine and 4 - chloromethyl benzoyl. The total yield was 41%.

Index Terms—Hydrogen peroxide bleaching, amide, activator, synthesis.

Yujie Ren is with the School of Chemistry and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China (e-mail: clab@sit. edu.cn).

[PDF]

Cite:Weijian Chen and Yujie Ren, "Develop New Approaches to the Synthesis of N, N, N-triethyl-4-[(Hexahydro-2-oxo-1H-azepin-1-yl) Carbonyl]-Bromine/Chloride," International Journal of Chemical Engineering and Applications vol. 5, no. 2 pp. 109-111, 2014.

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