Abstract—Herein, we report a series of low-molecular-weight hydrogelators and prove that the phenyl-perfluorophenyl pair in the structure of the hydrogelators can be used to promote the formation of the supramolecular hydrogels in physiological condition. Further spectroscopic study indicates the aromatic-aromatic and hydrogen-bonding interactions might be the major driving force behind the self-assembly of the nanostructured hydrogels. Biocompatible experiments of the hydrogelators were carried out on HeLa and MCF-7 cells which indicate the newly discovered hydrogelators are potential biomaterials.
Index Terms—Phenyl-perfluorophenyl pair, hydrogel, nanofiber, biomaterials.
Yu-Chun Lin, Shu-Min Hsu, Jui-Wen Chang, Yu-Hao Liu and Hsin-Chieh Lin are with the Department of Materials Science and Engineering, National Chiao Tung University, Taiwan (e-mail: hclin45@ nctu.edu.tw).
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Cite: Yu-Chun Lin, Shu-Min Hsu, Jui-Wen Chang, Yu-Hao Liu, and Hsin-Chieh Lin, "Self-Assembled Nanomaterials Based on Perfluorophenyl-Capped Dipeptides," International Journal of Chemical Engineering and Applications vol. 6, no. 2, pp. 81-85, 2015.
