Abstract—
Saccharum spontaneum Linn. (Fam. Poaceae) root extract have been pre-formulated into a cream and evaluated for its antibacterial and anti-inflammatory activities. Phytochemical screening done on the lyophilized plant extract have shown the presence of carbohydrates, glycosides, alkaloids, tannins and flavonoids. Antibacterial activities of the root extract and pre-formulated cream were evaluated by Kirby-Bauer Disk Diffusion Method against three microorganisms, namely,
Staphylococcus aureus,
Staphylococcus epidermidis, and
Pseudomonas aeruginosa. Likewise, the pre-formulated cream was evaluated for its anti-inflammatory activity using mice injected with 0.1 mL of 1% carrageenan solution to induce inflammation. The degree of inflammation was measured using a digital Vernier caliper at 0, 1, 2, and 3 hours after the stimulus was made. Evaluation results showed that the pre-formulated 2% root extract cream of the plant possess anti-inflammatory activity rather than antibacterial activity.
Index Terms—Antibacterial, anti-inflammatory, Kirby-Bauer disk diffusion method, S. spontaneum Linn. cream.
A. M. R. Lapuz, R. D. A. Arabiran, T. M. Sembrano, J. R. Albaniel, and J. C. Paet are with Adamson University, San Marcelino St., Ermita, Manila, Philippines, Filipino.
H. A. Maini is with Adamson University, San Marcelino St., Ermita, Manila, Philippines (e-mail: hedymaini@yahoo.com).
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Cite: A. M. R. Lapuz, R. D. A. Arabiran, T. M. Sembrano, J. R. Albaniel, J. C. Paet, and H. A. Maini, "Preformulation and Evaluation of Antibacterial and Anti-Inflammatory Activities of Saccharum spontaneum Linne Root Extract Cream," International Journal of Chemical Engineering and Applications vol. 7, no. 3, pp. 204-208, 2016.
