Abstract—Hydroquinone is polyphenol compound which was used as antioxidant. In this study, the hydroquinone was synthesized via aldol condensation between 1,4-cyclohexanedione and cinnamaldehyde which was extracted from the bark of Cinnamomum verum J.Presl by stream distillation and using LiCl as a catalyst in pyridine. The hydroquinone derivatives showed the dark brown crystal with Rf 0.50 (hexane : ethyl acetate : methanol 5 : 4 : 1). These products were characterized by FT-IR spectroscopy which showed spectrum at 3300 - 3500 cm-1 (O-H stretching), 3025 cm-1 (C-H stretching of aromatic), 1660 cm-1 (C=C stretching of alkene) and 1450, 1502 cm-1 (C=C stretching of aromatic), respectively. The characterization by 1H-NMR spectroscopy expressed 1H-NMR (ppm): 9.70 (d, 2H, OH), 6.35-7.56 (m, 8H, aromatic protons) and 3.50 (d, 2H, -CH2-), respectively. The synthesized product was tested the antioxidant activity by using DPPH radical scavenging assay and the IC50 was done by spectrophotometric assay method compared with standard gallic acid. The antioxidant activity revealed that IC50 were 14.15 ppm.
Index Terms—Cinnamaldehyde, antioxidant, hydroquinone derivatives, Cinnamomum verum J.Presl.
Uthumporn Kankeaw is with the Maejo University, Chiang Mai, Thailand (e-mail: mooeed@hotmail.com).
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Cite: Uthumporn Kankeaw and Ekkalak Masong, "The Antioxidant Activity from Hydroquinone Derivatives by the Synthesis of Cinnamomium Verum J.Presl Bark’s Extracted," International Journal of Chemical Engineering and Applications vol. 6, no. 2, pp. 91-95, 2015.
